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Douglas Lauffenburger, Ph.D.

AIMBE College of Fellows Class of 1992
For a pioneering role in developing cellular bioengineering through research and training in the area of receptor-mediated cell behavior.

A Breakthrough in Endometriosis Research

Via MIT Libraries News | February 26, 2014

Over the years Linda Griffith has undergone many surgeries for endometriosis, a condition in which tissue that normally grows in the uterus is found elsewhere in the body and can cause lesions, inflammation, and infertility. The disease is poorly understood, and so it made sense to Griffith, a professor of biological and mechanical engineering, to start researching it. In a paper published earlier this month, Griffith and colleagues, including bioengineering professor Douglas Lauffenburger, studied pelvic fluid from women with endometriosis and in about a third they found elevated levels of a group of immune system proteins. The work is an early step towards classifying the disease and, eventually, finding new treatments for it. “We’re not claiming we found a mechanism — the mechanism for endometriosis,” Griffith told the Boston Globe. “We have found a very convincing approach to understand an immune network.”

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