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Sabee Molloi, Ph.D.

AIMBE College of Fellows Class of 2015
For outstanding contributions to development of techniques for quantification of coronary artery lumen volume and blood flow using digital angiography

Efficacy of FPA in swine models could open the door for more accurate CAD testing in humans

Via Cardiovascular Business | October 27, 2017

A new lab technique could cut testing time and improve the accuracy of coronary artery disease (CAD) diagnoses according to new research published in Radiology.

First-pass analysis (FPA) technology could change the field of CAD diagnosis, Sabee Molloi, PhD, and co-authors wrote in the study, and eliminate the need for less accurate, more copious tests like fractional flow reserves, cardiac MRIs, single-photon emission CTs or PET scans. FPA combines computed tomographic (CT) angiography and dynamic CT perfusion data by using just two whole-heart volume scans and one contrast material injection. Molloi and colleagues found FPA to be a valuable method to enable accurate, low-dose vessel-specific morphologic and physiologic assessment of CAD in six swine models.

Unlike other testing techniques, FPA indicates good detection of microsphere perfusion values of less than 1 mL/min/g at maximal hyperemia in the left anterior descending artery (LAD), Molloi et al. explained. The technique also measures quantitative perfusion in the left circumflex artery, right coronary artery and all three coronary arteries combined, while limiting testing to just two first-pass volume scans and one injection… Continue reading.

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Sabee Molloi, Ph.D. To be Inducted into Medical and Biological Engineering Elite

Via AIMBE | March 5, 2015

WASHINGTON, D.C.— The American Institute for Medical and Biological Engineering (AIMBE) has announced the pending induction of Sabee Molloi, Ph.D., Professor and Vice Chairman of Research, Radiological Sciences, Medicine (Cardiology), Biomedical Engineering, Electrical Engineering and Computer Sciences, University of California, Irvine, to its College of Fellows. Dr. Molloi was nominated, reviewed, and elected by peers and members of the College of Fellows For outstanding contributions to development of techniques for quantification of coronary artery lumen volume and blood flow using digital angiography.

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