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Fellowbook News

AIMBE Fellowbook collects news stories highlighting the members of the AIMBE College of Fellows. Read the latest stories, jump to the College Directory, or search below to find the newest research, awards, announcements and more for the leaders of the medical and biological engineering community.

 

 

Advanced fabrication of biosensor on detection of Glypican-1 using S-Acetylmercaptosuccinic anhydride (SAMSA) modification of antibody

Chung-Chiun Liu | Via Nature | September 10, 2018

Abstract Glypican-1 (GPC-1) has been recognized as biomarker of pancreatic cancer. Quantification of GPC-1 level is also pivotal to breast cancer and prostate cancer’s patients. We hereby report the first biosensor for GPC-1 detection. Instead of using crosslinking technique and surface immobilization of antibody, we applied a novel method for biosensor fabrication, using S-Acetylmercaptosuccinic anhydride […]

NIH selects Bruce Tromberg, Ph.D., to lead the National Institute on Biomedical Imaging and Bioengineering (NIBIB)

Bruce Tromberg | Via NIBIB | September 6, 2018

National Institutes of Health Director Francis S. Collins, M.D., Ph.D., has selected Bruce J. Tromberg, Ph.D., as director of the National Institute of Biomedical Imaging and Bioengineering (NIBIB). A pioneering leader in the field of biophotonics, Dr. Tromberg is currently a professor at the University of California at Irvine (UCI), with dual appointments in the […]

A homing system targets therapeutic T cells to brain cancer

Rakesh Jain | Via Nature | September 5, 2018

Abstract Successful T cell immunotherapy for brain cancer requires that the T cells can access tumour tissues, but this has been difficult to achieve. Here we show that, in contrast to inflammatory brain diseases such as multiple sclerosis, where endothelial cells upregulate ICAM1 and VCAM1 to guide the extravasation of pro-inflammatory cells, cancer endothelium downregulates […]

Organic, Transparent, but Robust- Biomimetic Cornea Implants

Jennifer Elisseeff | Via Advanced Science News | September 3, 2018

The human eye is a marvelous organ that owes its performance to a lot of specialized components. The outermost of those, and seemingly simplest, is the cornea. The German word for it, “Hornhaut” (callused skin) already hints at one key function of the cornea – protection of the eye. However, actual callus, being as intransparent […]

New Cancer Treatment Uses Enzymes to Boost Immune System and Fight Back

George Georgiou | Via The University of Texas at Austin | August 30, 2018

Researchers at The University of Texas at Austin have developed a new approach to treating cancer using enzyme therapy. The enzyme, PEG-KYNase, does not directly kill cancer cells but instead empowers the immune system to eradicate unwanted cells on its own. PEG-KYNase is designed to degrade kynurenine, a metabolite produced by numerous tumors that suppresses […]

Decoding the Brain

Karen Moxon | Via UC Davis | August 30, 2018

In the last decade, researchers in academia and the technology sector have been racing to unlock the potential of artificial intelligence. In parallel with federally-funded efforts from the National Institutes of Health and the National Science Foundation, heavy-hitters such as Microsoft, Facebook and Google are deeply invested in artificial intelligence. As part of the BRAIN Initiative, […]

Scientists alter membrane proteins to make them easier to study

Shuguang Zhang | Via MIT | August 27, 2018

About 30 percent of the proteins encoded by the human genome are membrane proteins — proteins that span the cell membrane so they can facilitate communication between cells and their environment. These molecules are critical for learning, seeing, and sensing odors, among many other functions. Despite the prevalence of these proteins, scientists have had difficulty […]

Mass. General study defines mechanisms behind focused-ultrasound-assisted treatment of brain tumors

Rakesh Jain | Via Massachusetts General Hospital | August 27, 2018

A study led by a team of Massachusetts General Hospital (MGH) investigators has analyzed, for the first time, the mechanisms underlying the use of focused ultrasound to improve the delivery of anti-cancer drugs across the blood brain barrier into brain tumors. Their report published in PNAS uses advanced microcopy techniques and mathematical modeling to track […]

One step closer to bioengineered replacements for vessels and ducts

Ali Khademhosseini | Via EurekAlert | August 24, 2018

A team of Brigham and Women’s Hospital researchers have developed a way to bioprint tubular structures that better mimic native vessels and ducts in the body. The 3-D bioprinting technique allows fine-tuning of the printed tissues’ properties, such as number of layers and ability to transport nutrients. These more complex tissues offer potentially viable replacements […]

Deep Learning Attacks Joint Degeneration and Osteoarthritis: Musculoskeletal Imaging Research Published in ‘Radiology’

Sharmila Majumdar | Via University of California, San Francisco | August 23, 2018

Deep learning has become a powerful tool in radiology in recent years. Researchers at the UC San Francisco Department of Radiology and Biomedical Imaging have started using deep learning methods to characterize joint degeneration and osteoarthritis, which will ultimately reduce the number of total joint replacements. In a recent paper published in Radiology (PubMed) they […]

Cleavage of the leptin receptor by matrix metalloproteinase–2 promotes leptin resistance and obesity in mice

Geert Schmid-Schoenbein | Via AAAS | August 22, 2018

R. Mazor, D. Friedmann-Morvinski, T. Alsaigh, O. Kleifeld, E. B. Kistler, L. Rousso-Noori, C. Huang, J. B. Li, I. M. Verma, G. W. Schmid-Schönbein Restoring leptin’s effects in obesity Obesity is the most common metabolic disease in the developed world. Although obese individuals have increased plasma concentrations of the anorexigenic hormone leptin, they are refractory […]

Dean Loboa named vice chancellor for Strategic Partnerships

Elizabeth Loboa | Via University of Missouri | August 22, 2018

University of Missouri Chancellor Alexander Cartwright appointed MU Engineering Dean Elizabeth Loboa as the vice chancellor for Strategic Partnerships during his campus address on Wednesday. She will hold the position in addition to her duties as dean. In this dual role, Loboa will be the primary MU contact for the UM System Precision Medicine Initiative, […]

Michele Grimm earns Fellow status from Biomedical Engineering Society

Michele Grimm | Via Wayne State University | August 21, 2018

The Biomedical Engineering Society (BMES) has elected Michele Grimm, associate professor of biomedical engineering at Wayne State University, to the BMES Class of 2018 Fellows, a distinguished group of biomedical engineers who demonstrate exceptional achievements and experience in the field as well as a history of active membership in the Society. The Class of 2018 […]

Rory Cooper is Driven to Solve Problems for Disabled People

Rory Cooper | Via AAAS | August 20, 2018

As a young man, facing life after suffering a spinal cord injury in a bicycling accident in 1980, AAAS Fellow and AAAS-Lemelson Invention Ambassador Rory Cooper wanted three things — to become an engineer, to be able to support a family, and to make a difference in the world. But he didn’t think he could […]

Proof-of-concept technique makes nanoparticles attractive for new medications

You Han Bae | Via MD Linx | August 9, 2018

Since the development of insulin to manage diabetes, pharmacists have longed to create an insulin pill. Past attempts have failed because insulin does not survive the harsh conditions of the GI system and cannot easily cross the GI wall. Researchers at University of Utah Health developed a proof-of-concept technology using nanoparticles that could offer a […]

Genetic Mutations of Appendix Cancer Identified, May Impact Treatment

Trey Ideker | Via UC San Diego | August 8, 2018

The rarity of appendix cancer, accounting for less than 1 percent of tumors that originate in the gastrointestinal tract, and the lack of scientific data for this disease means that current treatment guidelines recommend applying therapies to people with appendix cancer that are intended for those with colon cancer. To understand why some patients with […]

Denali Therapeutics Appoints Dana Andersen, Ph.D., as Chief Technical and Manufacturing Officer

Dana Andersen | Via GlobeNewsWire | August 7, 2018

Denali Therapeutics, a biopharmaceutical company developing a broad portfolio of product candidates for neurodegenerative diseases, today announced that Dr. Dana Andersen has joined the company as Chief Technical and Manufacturing Officer. Dr. Andersen joins Denali from Genentech, where he served in various roles for nearly 23 years, working most recently as Vice President and Global […]

Gilda Barabino earns second national award this summer

Gilda Barabino | Via CCNY | August 1, 2018

The National Organization for the Professional Advancement of Black Chemists and Chemical Engineers presents its 2018 Dr. Joseph N. Cannon Award for Excellence in Chemical Engineering to Gilda A. Barabino, dean of The City College of New York’s Grove School of Engineering this fall. The award recognizes her excellent achievements in chemical engineering. Barabino will […]

Inexpensive biology kits offer hands-on experience with DNA

James Collins | Via MIT | August 1, 2018

To help students gain a better grasp of biological concepts, MIT and Northwestern University researchers have designed educational kits that can be used to perform experiments with DNA, to produce glowing proteins, scents, or other easily observed phenomena. Biology teachers could use the BioBits kits to demonstrate key concepts such as how DNA is translated […]