image_alt_text
2

Fellowbook News

AIMBE Fellowbook collects news stories highlighting the members of the AIMBE College of Fellows. Read the latest stories, jump to the College Directory, or search below to find the newest research, awards, announcements and more for the leaders of the medical and biological engineering community.

 

 

Autonomous Medical Intervention Extends ‘Golden Hour’ for Traumatic Injuries with Emergency Air Transport

Ronald Poropatich | Via University of Pittsburgh | May 24, 2024

For the first time, a closed loop, autonomous intervention nearly quadrupled the “golden hour” during which surgeons could save the life of a large animal with internal traumatic bleeding while in emergency ground and air transport. This breakthrough in trauma care, announced today in Intensive Care Medicine Experimental by physician-scientists at the University of Pittsburgh […]

pDNA Isoforms Assessed by Microfluidic Electrophoresis

Anubhav Tripathi | Via Genetic Engineering & Biotechnology News | May 22, 2024

Increased demands for plasmid DNA (pDNA) for emerging nucleic acid-based vaccines and therapies exacerbate the need to remove bottlenecks from pDNA production. For industry, the problem has been that as pDNA is synthesized and purified, the plasmids sometimes come out of their supercoiled isoform. In therapeutics, the resulting heterogeneous sequence mixtures and uncontrolled transcripts may […]

GLP-1s not tied to higher risk for surgical complications for adults with diabetes

David Klonoff | Via Healio | May 22, 2024

On June 29, 2023, the American Society of Anesthesiologists released consensus-based guidance recommending people who use GLP-1 receptor agonist drugs stop using them before surgery. Adults receiving daily GLP-1s were advised to stop the day of surgery, and those using a weekly GLP-1 were asked to stop therapy 7 days before surgery. However, David C. […]

Nano Drug Accelerates Diabetic Wound Healing in Mice

Yizhou Dong | Via Mount Sinai | May 20, 2024

Novel lipid nanoparticle-mRNA regimen reverses inflammation and aids recovery Researchers at the Icahn School of Medicine at Mount Sinai have designed a regenerative medicine therapy to speed up diabetic wound repair. Using tiny fat particles loaded with genetic instructions to calm down inflammation, the treatment was shown to target problem-causing cells and reduce swelling and […]

New technique bioprints live cells inside the body using ultrasonic waves

Shulamit Levenberg | Via Israel 21c | May 9, 2024

Revolutionary acousto-printing method can be used to circumvent invasive surgery, and has a wide array of potential applications. A new drug delivery and tissue implantation technique utilizing ultrasound waves as an alternative to surgery has been developed in the Stem Cell and Tissue Engineering Lab of Prof. Shulamit Levenberg at the Technion-Israel Institute of Technology. […]

Researchers Engineer Yeast to Deliver Drugs, Reduce Inflammation for Possible Inflammatory Bowel Disease Treatment

Juliane Nguyen | Via UNC Healthcare | May 7, 2024

Inflammatory bowel disease (IBD) is a complex condition that requires individualized care to meet the needs of the patient’s current disease state. With available medications sometimes causing serious side effects or losing their efficacy over time, many researchers have been exploring new, more targeted ways of delivering medications or other beneficial compounds, such as probiotics. […]

Stretchable skin could give caregiving robots a more human touch

Nanshu Lu | Via McKnights Senior Living | May 6, 2024

Newly developed stretchable electronic skin soon might give robots and other devices the same softness and touch sensitivity as human skin. This could prove especially promising for care of the aging, where a soft touch can make a huge difference. The new stretchable e-skin was developed by researchers at the University of Texas at Austin. […]

Aligned ‘noodles’ could pave way for lab-grown biological tissue

Jeffrey Hartgerink | Via Futurity | May 6, 2024

The development of a new fabrication process to create aligned nanofiber hydrogels could offer new possibilities for tissue regeneration after injury and provide a way to test therapeutic drug candidates without the use of animals. Jeffrey Hartgerink, professor of chemistry and bioengineering at Rice University and colleagues, developed peptide-based hydrogels that mimic the aligned structure […]

Refined AI Approach Improves Noninvasive BCI Performance

Bin He | Via Carnegie Mellon University | May 2, 2024

Pursuing a viable alternative to invasive brain-computer interfaces (BCIs) has been a continued research focus of Carnegie Mellon University’s He Lab. In 2019, the group used a noninvasive BCI to successfully demonstrate, for the first time, that a mind-controlled robotic arm had the ability to continuously track and follow a computer cursor. As technology has […]

U of M study finds metformin reduces COVID-19 viral load, viral rebound

David Odde | Via EurekAlert | May 2, 2024

A team of University of Minnesota researchers found that metformin, a drug commonly used to treat diabetes, can decrease the amount of COVID-19 virus in the body and lower the chances of the virus coming back strongly after initial treatment. The study was published in Clinical Infectious Diseases. A higher viral load — the amount […]

Synthetic Plugs Offer Alternative to Total Knee Replacements

Melissa Grunlan | Via Texas A&M University | April 30, 2024

Dr. Melissa Grunlan is developing synthetic plugs for patients suffering from chronic knee pain or disabilities that would avoid total knee replacements. Osteochondral defects (OCDs) can cause damage to cartilage and underlying bone, leading to chronic pain and loss of joint function. Depending on the extent of damage, individuals must undergo surgical treatment, the most […]

An electrifying discovery may help doctors deliver more effective gene therapies

Susan Hagness | Via University of Wisconsin–Madison | April 30, 2024

In an effort to improve delivery of costly medical treatments, a team of researchers in electrical engineering at the University of Wisconsin–Madison has developed a stimulating method that could make the human body more receptive to certain gene therapies. The researchers exposed liver cells to short electric pulses — and those gentle zaps caused the […]

Researchers create new, stronger way to repair lining of brain and spinal cord

David Mooney | Via The Highland County Press | April 26, 2024

Researchers have developed a more durable way to repair the dural membrane (dura) that lines the brain and spinal cord. The strong and highly adhesive hydrogel called Dural Tough Adhesive (DTA) solves key problems that may happen when repairing the dural membrane lining after trauma or surgery. The dural membrane is the outermost of three […]

Smart nanoparticles may be able to deliver drugs to heart after heart attack

Jianjun Guan | Via Washington University in St. Louis | April 25, 2024

Guan creates custom nanoparticles to fight inflammation, fibrosis Every 40 seconds, someone in the United States has a heart attack, according to the U.S. Centers for Disease Control and Prevention, and about 300,000 of those do not have surgery afterward to restore blood flow. These patients rely on drugs to reduce inflammation and inhibit scar […]

Circadian rhythms can influence drugs’ effectiveness

Sangeeta Bhatia | Via MIT | April 24, 2024

MIT researchers find circadian variations in liver function play an important role in how drugs are broken down in the body. Giving drugs at different times of day could significantly affect how they are metabolized in the liver, according to a new study from MIT. Using tiny, engineered livers derived from cells from human donors, […]

Researchers evaluate lung cancer treatment that can be inhaled

Ke Cheng | Via Healio | April 24, 2024

Researchers at Columbia University’s Herbert Irving Comprehensive Cancer Center are investigating a lung cancer treatment that can be delivered directly to the lungs. The treatment, which involves the inhalation of interleukin-12 (IL-12) messenger RNA, uses nanobubbles to facilitate local delivery to the lungs with fewer off-target side effects. Results of a preclinical study, published in […]

LeDuc named 2023 AAAS Fellow

Phil LeDuc | Via Carnegie Mellon University | April 22, 2024

Philip LeDuc, a professor in the Department of Mechanical Engineering, has been named a 2023 Fellow for the American Association for the Advancement of Science (AAAS). He is being recognized for his outstanding research contributions in “experimental cellular and molecular mechanics, biologically inspired engineered approaches, and global challenges both medical and nature inspired with integrated […]

Engineered Peptides Stimulate Antitumor Immune Responses in Mice

Betty Kim | Via Genetic Engineering & Biotechnology News | April 22, 2024

Researchers have designed a new method for developing immunotherapy drugs using engineered peptides to elicit a natural immune response inside the body. More specifically, they showed, in antigen presenting cells, that “the hydrophobicity, electrostatic charge, and secondary conformation of helical polypeptides can be optimized to stimulate innate immune pathways via endoplasmic reticulum stress.” In preclinical […]

Novel theranostic tool allows for noninvasive identification and treatment of ovarian cancer

Jason Lewis | Via EurekAlert | April 4, 2024

A new radiotheranostic system has the ability to detect and treat ovarian cancer noninvasively, according to new research published in the April issue of The Journal of Nuclear Medicine. Combining the highly specific huAR9.6 antibody with PET and therapeutic radionuclides, this theranostic platform may provide more personalized treatment to improve health outcomes for ovarian cancer […]