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Fellowbook News

AIMBE Fellowbook collects news stories highlighting the members of the AIMBE College of Fellows. Read the latest stories, jump to the College Directory, or search below to find the newest research, awards, announcements and more for the leaders of the medical and biological engineering community.

 

 

Gene Loss Enhances Metastasis and Cancer Progression

Shana Kelley | Via Northwestern University | September 29, 2022

Investigators have discovered that the loss of the gene SLIT2 in circulating tumor cells regulates metastasis of prostate cancer tumors, according to a Northwestern Medicine study published in Science Advances. Metastasis accounts for most cancer-related deaths, yet its underlying mechanisms have remained poorly understood despite recent advances in cancer treatments and care… Continue reading.

Breaking through the mucus barrier

Robert Langer | Via MIT | September 28, 2022

A capsule that tunnels through mucus in the GI tract could be used to orally administer large protein drugs such as insulin. One reason that it’s so difficult to deliver large protein drugs orally is that these drugs can’t pass through the mucus barrier that lines the digestive tract. This means that insulin and most […]

Growing Human Kidneys in a Lab – Scientists Have Made a Significant Breakthrough

Joseph Bonventre | Via Scitech Daily | September 26, 2022

One in nine adults worldwide has some kind of kidney disease, and kidney failure is becoming more common everywhere. Growing functional kidney tissue in a lab could accelerate kidney disease treatments and restore kidney function. In humans, the kidney forms naturally as a consequence of two building blocks: metanephric mesenchyme and ureteric bud. Seven years […]

Researchers design treatment to protect bones during cancer therapy

Sudipta Seal | Via Phys.org | September 26, 2022

University of Central Florida material sciences engineers Melanie Coathup and Sudipta Seal have designed a cerium oxide nanoparticle—an artificial enzyme—that protects bones against damage from radiation. The nanoparticle has also shown abilities to improve bone regeneration, reduce loss of blood cells and help kill cancer cells. Their study, a collaboration with Oakland University, North Carolina […]

Microscopic Robots in the Lungs Treat Bacterial Pneumonia in Mice

Liangfang Zhang | Via Genetic Engineering & Biotechnology News | September 23, 2022

The last decade has brought a lot of attention to the use of microscopic robots (microrobots or nanorobots) for biomedical applications. Now, nanoengineers have developed microrobots that can swim around in the lungs and deliver medication to be used to treat bacterial pneumonia. A new study shows that the microrobots safely eliminated pneumonia-causing bacteria in […]

Gang Han and colleagues develop superfluorescence, light-emitting, nanocrystal alternative to lasers

Gang Han | Via UMass Chan Medical School | September 22, 2022

Research may lead to a high-quality, nanosized, clean light source for biomedical applications and beyond Researchers at UMass Chan Medical School and North Carolina State University have developed a superfluorescence crystal nanoparticle that uses near-infrared light, a wave-length of light beyond what humans can see, to safely produce laser-quality light at room temperature. This discovery, […]

Shutting down backup genes leads to cancer remission in mice

Xiongbin Lu | Via University of Michigan | September 21, 2022

Cancer cells delete DNA when they go to the dark side, so a team of doctors and engineers targeted the ‘backup plans’ running critical cell functions The way that tumor cells enable their uncontrolled growth is also a weakness that can be harnessed to treat cancer, researchers at the University of Michigan and Indiana University […]

Student success, collaborations highlight Wodicka’s legacy at Purdue

George Wodicka | Via Purdue University | September 21, 2022

Culture of innovation helped distinguish biomedical engineering program Simply saying George Wodicka is a big thinker would undersell what he accomplished in two-plus decades leading Purdue’s biomedical engineering program. His thinking has been bigger than big, transforming a small research center into the renowned Weldon School of Biomedical Engineering, whose work impacts millions of patients […]

Laser light offers new tool for treating bone cancer

Lihong Wang | Via CalTech | September 19, 2022

Label-free intraoperative histology of bone tissue via deep-learning-assisted ultraviolet photoacoustic microscopyOf the many ways to treat cancer, the oldest, and maybe most tried and true, is surgery. Even with the advent of chemotherapy, radiation therapy, and more experimental treatments like bacteria that seek and destroy cancer cells, cancers, very often, simply need to be cut […]

Painless, Bloodless Tattoos Possible With New Microneedle Technique

Mark Prausnitz | Via Everyday Health | September 19, 2022

Tattoos may seem like they’re everywhere, and no longer taboo. But widespread medical use of tattoos has been limited because of the need for repeated needle injections that can be painful and carry risks of bleeding and infection. Now scientists have developed a way to avoid these deterrents: a tattoo patch containing microscopic needles that […]

Expert in Engineered Cell-Based Cancer Therapies Appointed USC Viterbi BME Chair

Peter Wang | Via University of Southern California | September 16, 2022

Peter Yingxiao Wang, a specialist in CAR T-cell cancer therapies, joins USC in January 2023 as the new chair of the Department of Biomedical Engineering. Research leader in the field of precision medicine, Professor Peter Yingxiao Wang, will join the USC Viterbi School of Engineering on January 1, 2023, as the new chair of the […]

Researchers Use Genetic Sequencing and Wastewater Analysis to Detect SARS-CoV-2 Variants and Monkeypox within Communities

Rob Knight | Via Dark Daily | September 12, 2022

Researchers surprised that process designed to detect SARS-CoV-2 also identifies monkeypox in wastewater Early information about an outbreak in a geographical region can inform local clinical laboratories as to which infectious agents and variants they are likely to see when testing patients who have symptoms. To that end, wastewater testing has become a rich source […]

Leading Tissue Regeneration Expert to Chair UVA’s Department of Biomedical Engineering

Shayn Peirce-Cottler | Via UVA Health | September 9, 2022

Shayn Peirce-Cottler, PhD, an international leader in biomedical engineering and a University of Virginia faculty member since 2004, has been named chair of UVA’s Department of Biomedical Engineering. She succeeds Frederick H. Epstein, PhD, who has served as chair of the Department of Biomedical Engineering – a joint program of UVA’s School of Medicine and […]

Analyzing the potential of AlphaFold in drug discovery

James Collins | Via MIT | September 6, 2022

Study finds computer models that predict molecular interactions need improvement before they can help identify drug mechanisms of action. Over the past few decades, very few new antibiotics have been developed, largely because current methods for screening potential drugs are prohibitively expensive and time-consuming. One promising new strategy is to use computational models, which offer […]

New Experimental Drug Protects Against Sudden Death

Samuel Wickline | Via SciTechDaily | September 5, 2022

The drug could pave the way for treatments for those who are at risk of sudden rupture due to abdominal aortic aneurysms. A study conducted by scientists at Washington University School of Medicine in St. Louis shows that an experimental drug therapy protects mice against sudden death brought on by the rupture of a major […]

AIMBE fellows Jeff Karp and Robert Langer are rapidly advancing a’ low-cost solution to curb trauma from accidental ingestion of button and coin cell batteries

Jeff Karp | Via AIMBE | August 31, 2022

Landsdowne Labs, a spinout from the Karp Lab at Brigham and Women’s Hospital and the Langer Lab at MIT, is rapidly advancing its first product, ChildLok– a technology designed to deactivate batteries following accidental ingestion, made possible by advanced material science. The Childlok technology has passed rigorous testing to date and is being readied for large scale […]

New technology offers pathways to finding treatments for kidney disease

Guy Genin | Via Washington University in St. Louis | August 31, 2022

Chronic kidney disease and eventual kidney failure are incurable diseases that affect 13% of the U.S. population, particularly those with high blood pressure and diabetes. These diseases degrade the “podocyte” cells of the kidney that maintain the body’s blood filtration system, eventually sending patients to dialysis. The search for effective treatments has been hampered because […]

Researchers in Boston Find COVID-19 Spike Protein Lingers in Long COVID-19 Patients

David Walt | Via Dark Daily | August 31, 2022

Viral reservoir could be behind persistence, says study, which also suggests a blood biomarker could be found for clinical laboratory testing Microbiologists and virologists working closely with physicians treating long COVID-19 patients will gain new insights in a study that found coronavirus spike protein in COVID-19 patients’ blood up to 12 months after diagnosis. The […]

This Mighty Brain Chip Is So Efficient It Could Bring Advanced AI to Your Phone

Gert Cauwenberghs | Via Singularity Hub | August 30, 2022

AI and conventional computers are a match made in hell. The main reason is how hardware chips are currently set up. Based on the traditional Von Neumann architecture, the chip isolates memory storage from its main processors. Each computation is a nightmarish Monday morning commute, with the chip constantly shuttling data to-and-fro from each compartment, […]

A key step toward growing human kidneys in the laboratory

Joseph Bonventre | Via Phys.org | August 30, 2022

Kidney disease affects one in nine adults globally and the incidence of kidney failure is steadily rising around the world. Being able to grow working kidney tissue in a laboratory could help accelerate medical treatments for kidney disease and restore kidney function. The kidney forms normally in humans as a result of two building blocks—metanephric […]