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Sanjiv Sam Gambhir, M.D., Ph.D.

AIMBE College of Fellows Class of 2006

Stanford develops novel PET tracer to ID most bacterial infections

Via Health Imaging | October 12, 2017

Bacteria are experts at mutating to become resistant to any antibiotic treatment. With no promise of stagnation, it is no wonder that the Centers for Disease Control and Prevention (CDC) has called for medical scientists to develop new novel diagnostics to detect and help regulate the treatment of infections and infectious diseases.

A new study featured in the October issue of The Journal of Nuclear Medicine describes how Stanford University scientists developed a novel imaging agent that could be used to detect most bacterial infections and monitor antibiotic treatment.

“We really lack tools in the clinic to be able to visualize bacterial infections,” explained Sanjiv Sam Gambhir, MD, PhD, and chair of the radiology department and director of Precision Health. “What we need is something that bacteria eat that your cells, so-called mammalian cells, do not. As it turns out, there is such an agent, and that agent is maltose, which is taken up only by bacteria because they have a transporter, called a maltodextrine transporter, on their cell wall that is able to take up maltose and small derivatives of maltose… Continue reading.

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Novel PET tracer identifies most bacterial infections

Via Medical Xpress.com | October 5, 2017

Stanford University medical scientists have developed a novel imaging agent that could be used to identify most bacterial infections. The study is the featured basic science article in The Journal of Nuclear Medicine’s October issue.

Bacteria are good at mutating to become resistant to antibiotics. As one way to combat the problem of antimicrobial resistance, the Centers for Disease Control and Prevention (CDC) has called for the development of novel diagnostics to detect and help manage the treatment of infectious diseases.

“We really lack tools in the clinic to be able to visualize bacterial infections,” explains Sanjiv Sam Gambhir, MD, PhD, chair of the Radiology Department and director of Precision Health and Integrated Diagnostics at Stanford University in California. “What we need is something that bacteria eat that your cells, so-called mammalian cells, do not. As it turns out, there is such an agent, and that agent is maltose, which is taken up only by bacteria because they have a transporter, called a maltodextrine transporter, on their cell wall that is able to take up maltose and small derivatives of maltose… Continue reading.

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Four Medical School Professors Elected Fellows Of AAAS

Via Stanford | December 1, 2014

Sanjiv “Sam” Gambhir, MD, PhD, professor and chair of radiology and director of the Canary Center for Cancer Early Detection at Stanford, was elected for his work in multimodal molecular imaging of living subjects.

In his work, Gambhir, who has a particular interest in cancer biology and gene therapy, combines advances in molecular and cell biology with those in biomedical imaging. He holds the Virginia and D. K. Ludwig Professorship in Cancer Research.

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