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Krishnendu Roy, Ph.D.

AIMBE College of Fellows Class of 2009
For leading contributions in biomaterials for immune system engineering especially for nucleic acid delivery, nanobiotechnology and stem cell therapeutics.

Krishnendu Roy Named New Robert A. Milton Chair at Georgia Tech

Via Twitter | September 24, 2015

Krishnendu Roy has been named the New Robert A. Milton Endowed Chair at the Parker H. Petit Institute for Bioengineering & Bioscience at the Georgia Institute of Technology effective October 1, 2015.

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Cells Prefer Nanodiscs Over Nanorods

Via Georgia Tech News Center | October 7, 2013

For years scientists have been working to fundamentally understand how nanoparticles move throughout the human body. One big unanswered question is how the shape of nanoparticles affects their entry into cells. Now researchers have discovered that under typical culture conditions, mammalian cells prefer disc-shaped nanoparticles over those shaped like rods.

Understanding how the shape of nanoparticles affects their transport into cells could be a major boost for the field of nanomedicine by helping scientists to design better therapies for various diseases, such as improving the efficacy and reducing side effects of cancer drugs.

In addition to nanoparticle geometry, the researchers also discovered that different types of cells have different mechanisms to pull in nanoparticles of different sizes, which was previously unknown. The research team also used theoretical models to identify the physical parameters that cells use when taking in nanoparticles.

“This research identified some very novel yet fundamental aspects in which cells interact with the shape of nanoparticles,” said Krishnendu Roy, who recently joined the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. Roy conducted this research at The University of Texas at Austin in collaboration with Profs. S. V. Sreenivasan and Li Shi, but is continuing the work at Georgia Tech.

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Cancer Researchers Get Crucial Funding

Via University of Texas at Austin | March 3, 2010

University of Texas at Austin engineering professors George Georgiou and Krishnendu Roy are working on ways to treat cancer with drugs.
Georgiou is developing new proteins for treating liver cancer. Roy is engineering systems for delivering vaccines for lymphoma.

And they have received funding from the Cancer Prevention and Research Institute of Texas (CPRIT) that will support critical links in getting their research from their laboratories to patients.

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