Martin L. Yarmush, M.D., Ph.D.

AIMBE College of Fellows Class of 1993
For the development of novel immunologic tools and for establishing long-term stable culture systems for use in artificial liver devices.

‘Lab-on-a-Chip’ Could Cut Costs of Sophisticated Diagnostic Tests

Via MDT | September 14, 2015

Rutgers engineers have developed a breakthrough device that can significantly reduce the cost of sophisticated lab tests for medical disorders and diseases, such as HIV, Lyme disease and syphilis.

The new device uses miniaturized channels and valves to replace “benchtop” assays – tests that require large samples of blood or other fluids and expensive chemicals that lab technicians manually mix in trays of tubes or plastic plates with cup-like depressions….

“The results are as sensitive and accurate as the standard benchtop assay,” said Martin Yarmush, the Paul and Mary Monroe Chair and Distinguished Professor of biomedical engineering at Rutgers and Ghodbane’s adviser.

Until now, animal research on central nervous system disorders, such as spinal cord injury and Parkinson’s disease, has been limited because researchers could not extract sufficient cerebrospinal fluid to perform conventional assays.

“With our technology, researchers will be able to perform large-scale controlled studies with comparable accuracy to conventional assays,” Yarmush said.