Researchers from the University of Wisconsin-Madison Department of Biomedical Engineering and Wisconsin Institute for Discovery (WID) have pioneered a new method to enhance the body’s disease-fighting T cells using advanced gene editing techniques. A new study published in the journal Frontiers in Bioengineering and Biotechnology suggests leveraging CRISPR technology as an innovative approach to making cancer treatments safer and more effective. Using a multiplexing technique, the team addresses key challenges in current cancer therapies that could significantly improve treatment outcomes.

“We have developed a new way to engineer immune cells to fight cancer more effectively. Think of it as reprogramming the body’s own soldiers (T cells) to recognize and attack cancer cells. We use a tool called CRISPR to make precise changes to the T cells without using viruses, making the process safer and potentially more effective,” says Krishanu Saha, an associate professor of biomedical engineering and faculty member at WID… Continue reading.