Sergei Maslov, Ph.D.

The human gut consists of a complex community of microbes that consume and secrete hundreds of small molecules—a phenomenon called cross-feeding. However, it is challenging to study these processes experimentally. A new study, published in Nature Communications, uses models to predict cross-feeding interactions between microbial species in the gut. Predictions from such computational methods could eventually help doctors get a more complete understanding of gut health.

The microbial community, or microbiome, of the gut is known to influence human health. Previous studies have focused on determining the types of microbes that are present. Unfortunately, this information is not enough to understand the microbiome.

“The gut environment is shaped by small molecules known as metabolites, which are excreted by the microbial community,” said Sergei Maslov (BCXT/CABBI), a professor of bioengineering and Bliss faculty scholar. “Although it is possible to measure these metabolites experimentally, it is cumbersome and expensive… Continue reading.

WASHINGTON, D.C. — The American Institute for Medical and Biological Engineering (AIMBE) has announced the election of Sergei Maslov, Ph.D., to its College of Fellows. Dr. Maslov was nominated, reviewed, and elected by peers and members of the College of Fellows for his contributions to computational biology including microbiome dynamics, microbial and viral ecology, genomics, and studies of complex biological networks.

The College of Fellows is comprised of the top two percent of medical and biological engineers in the country. The most accomplished and distinguished engineering and medical school chairs, research directors, professors, innovators, and successful entrepreneurs comprise the College of Fellows. AIMBE Fellows are regularly recognized for their contributions in teaching, research, and innovation. AIMBE Fellows have been awarded the Nobel Prize, the Presidential Medal of Science and the Presidential Medal of Technology and Innovation and many also are members of the National Academy of Engineering, National Academy of Medicine, and the National Academy of Sciences… Continue reading.

A mathematical model created by IGB researchers could help scientists better understand an intriguing characteristic of microbial communities: their ability to achieve stability despite being so diverse.

Microbial communities are groups of microorganisms that exist in a variety of environments — in the soil, in the oceans, and in our bodies. Though these communities are complex and diverse, they are able to form stable ecosystems… Continue reading.