Anirban Sen Gupta, Ph.D.

More than two million platelet units are needed in the United States every year. However, natural platelets aren’t always available or portable, have a high risk of contamination, and have a limited shelf life of 5 to 7 days, prompting research over the last several decades into synthetic alternatives.

For that reason, alternatives have been sought through the design of synthetic platelets. These could help save lives by rapidly stabilizing clots to reduce blood loss from traumatic injuries. A new effort has engineered platelet-mimicking procoagulant nanoparticles (PPNs) that help generate a protein mesh that acts as a natural netting to stabilize blood clots and help stop bleeding in an injury-responsive manner. Studies in rodents demonstrated that PPNs provided hemostatic efficacy in animal models of hemorrhage. If proven safe and efficient in clinical trials, the technology would bolster the scientists’ advances in a decade-long effort to develop and optimize what they call synthetic platelet surrogates… Continue reading.

WASHINGTON, D.C. — The American Institute for Medical and Biological Engineering (AIMBE) has announced the election of Anirban Sen Gupta, Ph.D., to its College of Fellows. Dr. Sen Gupta was nominated, reviewed, and elected by peers and members of the College of Fellows for outstanding contributions in biomaterials science research and education with a focus on hemostasis, hemocompatibility, wound healing, and point-of-care devices.

The College of Fellows is comprised of the top two percent of medical and biological engineers in the country. The most accomplished and distinguished engineering and medical school chairs, research directors, professors, innovators, and successful entrepreneurs comprise the College of Fellows. AIMBE Fellows are regularly recognized for their contributions in teaching, research, and innovation. AIMBE Fellows have been awarded the Nobel Prize, the Presidential Medal of Science and the Presidential Medal of Technology and Innovation and many also are members of the National Academy of Engineering, National Academy of Medicine, and the National Academy of Sciences… Continue reading.