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World’s Smallest Pacemaker is Activated by Light

Igor Efimov | Via Northwestern University | April 2, 2025

Northwestern University engineers have developed a pacemaker so small that it can fit inside the tip of a syringe — and be non-invasively injected into the body, according to a new study published in Nature.

Although it can work with hearts of all sizes, the pacemaker is particularly well-suited to the tiny, fragile hearts of newborn babies with congenital heart defects.

Smaller than a single grain of rice, the pacemaker is paired with a small, soft, flexible, wireless, wearable device that mounts onto a patient’s chest to control pacing. When the wearable device detects an irregular heartbeat, it automatically shines a light pulse to activate the pacemaker. These short pulses—which penetrate through the patient’s skin, breastbone and muscles — control the pacing… Continue reading.

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