Coaxial Electrospinning Creates New Platform for Treating Glioblastoma

Henry Brem | Via Genetic Engineering & Biotechnology News | December 4, 2019

Andrew Steckl, PhD, an Ohio eminent scholar and professor of electrical engineering in the University of Cincinnati’s (UC) college of engineering and applied science, working with researchers from Johns Hopkins University, said they have developed a new treatment for glioblastoma multiforme (GBM), an aggressive form of brain cancer. Steckl’s nanoelectronics laboratory applied an industrial fabrication process called coaxial electrospinning to form drug-containing membranes.

The treatment, which is implanted directly into the part of the brain where the tumor is surgically removed, can deliver a safe and effective dose of medicine for brain tumors without exposing patients to toxic side effects from traditional chemotherapy, according to the scientists, who published their study (“Multi-layered core-sheath fiber membranes for controlled drug release in the local treatment of brain tumor”) in Nature Scientific Reports… Continue reading.