Michael Ladisch, Ph.D.

AIMBE College of Fellows Class of 1994
For contributions to the discovery and development of new separating agents, protein purification systems, and scale-up of chromatographic separations of biopharmaceutical products.

Doppler Used in Novel Microbial Assay To Tell a Friend from a Foe

Via Genetic Engineering & Biotechnology News | March 2, 2021

You must have noticed the sudden change in pitch of a siren on a police car zooming past. That’s the Doppler effect. Scientists at Purdue University have now used the Doppler effect to look inside living cells in a novel approach to detect pathogens and treat infections.

In this unique method, Doppler is used to quickly track metabolic activity in cells and can be used to detect pathogenic microbes in food, water, and other environments and identify treatments for antibiotic-resistant bacteria.

These findings are published in the article “Doppler imaging detects bacterial infection of living tissue,” in the journal Communications Biology by a team of researchers at Purdue University including David Nolte, PhD, professor of physics and Astronomy, John Turek, PhD, professor of basic medical sciences, Eduardo Ximenes, PhD, research scientist in the department of agricultural and biological engineering, and Michael Ladisch, PhD, professor of agricultural and biological Engineering… Continue reading.