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Paul Yager, Ph.D.

AIMBE College of Fellows Class of 2000

Coronavirus Testing Shouldn’t Be This Complicated

Via The Verge | March 30, 2020

Engineers have the technology to make it better

The US reported its first confirmed case of COVID-19 on January 21st. Eight weeks later, there still aren’t enough tests for the virus available for everyone who needs them. “It is a failing,” said Anthony Fauci, director of the National Institutes of Allergy and Infectious Diseases, at a House briefing last week. “The system is not really geared to what we need right now.”

People who are sick or have been in contact with sick people are struggling to get tested. Until last week, the number of tests that could be run per day in the United States was limited to around 7,000. Labs are struggling to get the supplies they need to meet the demand.

PCR is the gold-standard testing platform for viruses because it’s highly sensitive, says Paul Yager, a professor in the department of bioengineering at the University of Washington — it can detect even a tiny amount of virus in a patient sample and is less likely to incorrectly have a negative result… Continue reading.

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Paul Yager Receives Over $4M To Continue Developing Paper-Based Diagnostic Device

Via U. of Washington | August 11, 2015

UW Bioengineering Professor Paul Yager has received $4,197,407 of funding from the U.S. Department of Defense/Defense Advanced Research Projects Agency (DARPA) to continue a project which aims to develop a small, paper-based device that could quickly test for infectious diseases in low-resource environments. With this new funding, Dr. Yager is the third-highest recipient of research funding amongst UW Medicine faculty in Q2 2015 (April-June), according to a July report from the UW Medicine Office of Research and Graduate Education.

This new award adds to nearly $14M of funding previously awarded to the project, Multiplexable Autonomous Disposables for Nucleic Acid Amplification Tests for LRSs (MAD NAAT). The MAD NAAT project investigates the potential applications of the 2-dimensional paper network (2DPN) for point-of care diagnosis of infectious disease. The project has seen rapid progress from an ambitious concept to its current iteration as a feasible platform with promising potential for broad applications.

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