Jeffrey Lotz, Ph.D.

UC San Francisco researchers have shown in studies of mice that high loads on the spine alter the physical structure and biologic activity of discs — the gel-filled cushions between bones in the spine.

“The findings should lead to improved treatments for one cause of low back pain, disc degeneration — a condition in which discs become dehydrated and inefficient at supporting forces in the spine,” according to Jeffrey Lotz, PhD, UCSF assistant professor and director of the orthopaedic bioengineering laboratory, department of orthopaedic surgery. “In addition, the research may allow us to define what is an appropriate or inappropriate load for the back to better protect workers from occupationally-related injury.”

Lotz presented his findings today (June 12) at the annual meeting of the International Society for the Study of the Lumbar Spine where he received the 1998 Volvo Award For Low Back Pain Research… Continue reading.