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Xiaohu Gao, Ph.D

AIMBE College of Fellows Class of 2013
For outstanding contributions to biomedical nanotechnology and molecular engineering, especially in the development of quantum dots and plasmonic nanoparticles for in-vivo imaging and multiplexed diagnostic applications.

UW Bioengineers Use Cholesterol Tag to Ease Proteins into Cells

Via University of Washington | June 28, 2020

Xiaohu Gao, professor of bioengineering, and his lab have developed a new, cholesterol-based tag system to bring imaging and disease-treating proteins directly into a live cell, bypassing the cell’s defenses. They reported their finding June 19 in Science Advances.

Traditionally, imaging and treatment of live cells has been limited to biomarkers on the cell’s surface, because the cell’s natural defenses block large biomolecules, such as proteins, from freely crossing the cell membrane. With the vast majority of desired imaging and disease targets located inside the cell, researchers have been working on methods to bypass this problem… Continue reading.