Sangyong Jon, Ph.D.

Anti-inflammatory nanoparticles mimic glycocalyx

Chronic inflammatory bowel disease (IBD), such as Crohn’s disease and ulcerative colitis, is on the rise worldwide. The benefits of current medications are limited by problematic side effects. In the journal Angewandte Chemie, a South Korean research team has now introduced a new method of treatment. It is based on nanoparticles that mimic a special carbohydrate layer (glycocalyx) located on inflamed bowel cells, and which trigger anti-inflammatory effects in the diseased sites in the intestine.

Stomach cramps and severe diarrhea, often accompanied by significant weight loss, are some of the symptoms repeatedly suffered by patients with IBD, often for weeks at a time. The causes of this condition remain unclear but seem to involve a malfunction of the immune system… Continue reading.

WASHINGTON, D.C.— The American Institute for Medical and Biological Engineering (AIMBE) has announced the pending induction of Sangyong Jon, Ph.D., Full Professor of Biological Sciences, Director of Global Research Lab, Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), to its College of Fellows. Dr. Jon was nominated, reviewed, and elected by peers and members of the College of Fellows For outstanding contributions to advancing biomimetic nanomaterials for drug delivery to improve or enable treatments of cancers and infectious diseases.