To advance the engineering of biology at the molecular and cellular levels, the National Science Foundation (NSF) has awarded $16 million for research to characterize the regulation of gene activity and expression, and to create strategies to modify those processes without altering the DNA sequence.
Chromatin — a combination of DNA, RNA and proteins within a cell’s nucleus — can be modified by attaching additional molecules. This can cause altered gene expression without actually changing the cell’s DNA. These so-called epigenetic changes can alter an organism’s traits, or phenotype, and may even be passed to offspring.
The NSF EFRI Chromatin and Epigenetic Engineering (CEE) investment will support potentially transformative research by eight interdisciplinary teams:
WASHINGTON, D.C.— The American Institute for Medical and Biological Engineering (AIMBE) has announced the pending induction of Emilia Entcheva, Ph.D., Professor of Biomedical Engineering, Biomedical Engineering, George Washington University, to its College of Fellows. Dr. Entcheva was nominated, reviewed, and elected by peers and members of the College of Fellows For pioneering work in cardiac optogeneticsspearheading the development and biophysical characterization of new bioengineering tools towards all-optical electrophysiology.