Juan G. Santiago, Ph.D.

Purigen Biosystems, Inc., a leading provider of next-generation technologies for extracting and purifying nucleic acids from biological samples, today announced the launch of the Ionic® FFPE Complete Purification Kit. Scientists are now able to consistently recover both DNA and RNA (mRNA and miRNA) simultaneously from formalin-fixed, paraffin-embedded (FFPE) tissue samples in a single workflow. Purigen is showcasing the advantages of the new kit during the virtual Advances in Genome Biology and Technology (AGBT) 2021 annual meeting.

Purigen’s dedicated FFPE to Pure DNA and FFPE to Pure RNA Kits enable scientists to purify and concentrate superior yields of DNA or RNA from precious samples, and the new Ionic FFPE Complete Purification Kit rounds out Purigen’s FFPE purification portfolio. With this addition, Purigen enables users of the Ionic system to simultaneously extract and purify high yields of DNA and RNA from the same FFPE section or scroll — all while using a streamlined workflow that reduces hands-on time by as much as 75% in comparison to manual column or bead-based methods. The combination of a simple workflow with a simultaneous extraction of DNA and RNA at high yield and quality enables researchers to maximize rare or precious FFPE samples… Continue reading.

Purigen Biosystems, Inc., a leading provider of next-generation technologies for extracting and purifying nucleic acids from biological samples, today announced the launch of the Ionic® Cells to Pure DNA Low Input Kit for researchers working with limited biological samples. The simplified and automated 60-minute workflow delivers high-quality DNA for the rapid investigation of genetic abnormalities or examination of disease treatment effects.

The Ionic Cells to Pure DNA Low Input Kit offers consistent recovery of DNA with yields near the theoretical maximum for as many as 100,000 down to as few as 10 cultured or sorted cells. Compared to leading column-based products, the new kit delivers up to twice the amount of DNA with a significantly higher proportion greater than 20 kb in length. Regardless of the input amount, the workflow is the same and does not require carrier RNA. The prepared DNA is ready for analysis by downstream techniques such as next-generation sequencing (NGS) or qPCR… Continue reading.

Purigen Biosystems, Inc., a leading provider of next-generation technologies for extracting and purifying nucleic acids from biological samples, today announced the launch of its Ionic™ Purification System. The small benchtop system utilizes the company’s core isotachophoresis (ITP) technology to extract, purify, and concentrate nucleic acids from biological samples in one hour with less than three minutes of hands-on time per sample. Purigen will unveil the new system and present data during the Association for Molecular Pathology (AMP) 2019 Annual Meeting and Expo.

The Ionic Purification System enables the automated extraction of nucleic acids with dramatically increased yields and improved purity from a wide range of sample types, including cultured or sorted cells and formalin-fixed, paraffin-embedded (FFPE) tissues. Biological samples are gently lysed and then loaded into the Ionic™ Fluidics Chip. The Ionic system then applies an electric field to the chip and the nucleic acids are isolated in their natural, native form using the company’s proprietary ITP technology. The nucleic acids are not denatured or dehydrated, and there is no binding or stripping from fixed surfaces. The process minimizes fragmentation and eliminates any bead or buffer contamination. The extracted nucleic acids are pure, abundant, and ready for analysis by any downstream technique such as next-generation sequencing or PCR… Continue reading.

WASHINGTON, D.C.— The American Institute for Medical and Biological Engineering (AIMBE) has announced the pending induction of Juan G. Santiago, Ph.D., Professor, Mechanical Engineering, Stanford University, to its College of Fellows. Dr. Santiago was nominated, reviewed, and elected by peers and members of the College of Fellows For outstanding contributions to fundamental understanding of electrokinetic phenomena impacting a wide range of applications spanning from energy to bioanalysis.