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Edward S. Boyden, Ph.D.

AIMBE College of Fellows Class of 2018
For breakthrough contributions to neuroengineering, including the development of optogenetics and expansion microscopy for mapping and controlling the brain.

Mapping the brain at high resolution

Via MIT | January 17, 2019

Researchers have developed a new way to image the brain with unprecedented resolution and speed. Using this approach, they can locate individual neurons, trace connections between them, and visualize organelles inside neurons, over large volumes of brain tissue.

The new technology combines a method for expanding brain tissue, making it possible to image at higher resolution, with a rapid 3-D microscopy technique known as lattice light-sheet microscopy. In a paper appearing in Science Jan. 17, the researchers showed that they could use these techniques to image the entire fruit fly brain, as well as large sections of the mouse brain, much faster than has previously been possible. The team includes researchers from MIT, the University of California at Berkeley, the Howard Hughes Medical Institute, and Harvard Medical School/Boston Children’s Hospital.

This technique allows researchers to map large-scale circuits within the brain while also offering unique insight into individual neurons’ functions, says Edward Boyden, the Y. Eva Tan Professor in Neurotechnology, an associate professor of biological engineering and of brain and cognitive sciences at MIT, and a member of MIT’s McGovern Institute for Brain Research, Media Lab, and Koch Institute for Integrative Cancer Research… Continue reading.

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Team invents method to shrink objects to the nanoscale

Via MIT | December 13, 2018

MIT researchers have invented a way to fabricate nanoscale 3-D objects of nearly any shape. They can also pattern the objects with a variety of useful materials, including metals, quantum dots, and DNA.

“It’s a way of putting nearly any kind of material into a 3-D pattern with nanoscale precision,” says Edward Boyden, the Y. Eva Tan Professor in Neurotechnology and an associate professor of biological engineering and of brain and cognitive sciences at MIT.

Using the new technique, the researchers can create any shape and structure they want by patterning a polymer scaffold with a laser. After attaching other useful materials to the scaffold, they shrink it, generating structures one thousandth the volume of the original… Continue reading.

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Dr. Edward Boyden Inducted into Medical and Biological Engineering Elite

Via AIMBE | April 10, 2018

WASHINGTON, D.C.—The American Institute for Medical and Biological Engineering (AIMBE) has announced the induction of Edward S. Boyden, Ph.D., Associate Professor, Media Lab and McGovern Institute, Departments of Biological Engineering and Brain and Cognitive Sciences, and Co-Director, Center for Neurobiological Engineering, Massachusetts Institute of Technology, to its College of Fellows. Dr. Boyden was nominated, reviewed, and elected by peers and members of the College of Fellows for breakthrough contributions to neuroengineering, including the development of optogenetics and expansion microscopy for mapping and controlling the brain.

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