For the first time, scientists are able to directly compare the different kinds of injury that mechanical ventilation causes to cells in the lungs.
In a new study, using a ventilator-on-a-chip model developed at The Ohio State University, researchers found that shear stress from the collapse and reopening of the air sacs is the most injurious type of damage.
This miniature “organ-on-a-chip” model simulates not only lung injury during mechanical ventilation, but also repair and recovery, in human-derived cells in real time, said co-lead author Samir Ghadiali, Ph.D., professor and chair of biomedical engineering at Ohio State… Continue reading.
WASHINGTON, D.C.—The American Institute for Medical and Biological Engineering (AIMBE) has announced the induction of Samir N. Ghadiali, Ph.D., Professor, Department of Biomedical Engineering, Department of Internal Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, The Ohio State University, to its College of Fellows. Dr. Ghadiali was nominated, reviewed, and elected by peers and members of the College of Fellows for outstanding contributions to the fields of Respiratory Biomechanics and Cellular Mechanobiology and leadership in Biomedical Engineering Education.