Kristala L.J. Prather, Ph.D.

Eight researchers, along with 13 additional alumni, are honored for significant contributions to engineering research, practice, and education.

Eight MIT researchers are among the 128 new members and 22 international members recently elected to the National Academy of Engineering (NAE) for 2025. Thirteen additional MIT alumni were also elected as new members.

One of the highest professional distinctions for engineers, membership in the NAE is given to individuals who have made outstanding contributions to “engineering research, practice, or education, including, where appropriate, significant contributions to the engineering literature” and to “the pioneering of new and developing fields of technology, making major advancements in traditional fields of engineering, or developing/implementing innovative approaches to engineering education.”

The eight MIT electees this year include:

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Kristala L. Prather ’94, the Arthur Dehon Little Professor and head of the Department of Chemical Engineering, was honored for the development of innovative approaches to regulate metabolic flux in engineered microorganisms with applications to specialty chemicals production… Continue reading.

Metabolic engineers have a problem: cells are selfish. The scientists want to use microbes to produce chemical compounds for industrial applications. The microbes prefer to concentrate on their own growth.

Kristala L. Jones Prather ’94 has devised a tool that satisfies both conflicting objectives. Her metabolite valve acts like a train switch: it senses when a cell culture has reproduced enough to sustain itself and then redirects metabolic flux—the movement of molecules in a pathway—down the track that synthesizes the desired compound. The results: greater yield of the product and sufficient cell growth to keep the culture healthy and productive… Continue reading.

WASHINGTON, D.C. — The American Institute for Medical and Biological Engineering (AIMBE) has announced the induction of Kristala L.J. Prather, Ph.D., Arthur D. Little Professor, Department of Chemical Engineering, Massachusetts Institute of Technology, to its College of Fellows.

Election to the AIMBE College of Fellows is among the highest professional distinctions accorded to a medical and biological engineer. The College of Fellows is comprised of the top two percent of medical and biological engineers. College membership honors those who have made outstanding contributions to “engineering and medicine research, practice, or education” and to “the pioneering of new and developing fields of technology, making major advancements in traditional fields of medical and biological engineering, or developing/implementing innovative approaches to bioengineering education.”

Dr. Prather was nominated, reviewed, and elected by peers and members of the College of Fellows for “pioneering research in metabolic engineering and synthetic biology towards the design, assembly and regulation of biosynthetic pathways.“