In an unexpected finding, a new study flips on its head researchers’ understanding of how precancerous pancreas lesions evolve into pancreatic cancer. The paradigm-changing discovery has tremendous implications for identifying people at higher risk of cancer or even, potentially stopping malignant transformation.
In a study just out in the American Association for Cancer Research’s journal Cancer Discovery, scientists from the University of Maryland School of Medicine and the University of Michigan combined cutting-edge technologies, including spatial transcriptomics and single-cell RNA sequencing, with advanced computational and bioinformatics approaches to precisely map the cellular architecture surrounding precancerous pancreas lesions that occur sporadically relative to those that are cancer-associated to learn how the lesions might progress to cancer… Continue reading.
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