AIMBE
A new study from scientists at UT Southwestern Medical Center demonstrates that a nanoparticle-based vaccine can safely eliminate both localized and metastatic tumors caused by human papillomavirus (HPV) in mice. The findings, published in Proceedings of the National Academy of Sciences (PNAS), introduce a “stimuli-responsive STING nanovaccine” that could eventually offer a new treatment avenue for patients with advanced HPV-related cancers.
“Our study provides a safe and effective way to treat cancers that have spread or cannot be surgically removed,” said senior author Jinming Gao, PhD, a professor at the Harold C. Simmons Comprehensive Cancer Center and in Biomedical Engineering, Cell Biology, Otolaryngology–Head & Neck Surgery, and Pharmacology at UT Southwestern. “Creating a nanovaccine for systemic use for metastatic cancers is not easy due to potential toxicity, but we have overcome those challenges with this new therapy… Continue reading.
