Frances H. Arnold, Ph.D.

AIMBE College of Fellows Class of 2001
For developing and advancing directed evolution of enzymes and pathways and its application to biochemical conversions.

Arnold Named Co-Chair of President-elect Biden’s Science and Technology Advisory Council

Via Caltech | January 15, 2021

President-elect Joe Biden has appointed Frances Arnold, Caltech’s Linus Pauling Professor of Chemical Engineering, Bioengineering and Biochemistry and director of the Donna and Benjamin M. Rosen Bioengineering Center, to the President’s Council of Advisors on Science and Technology (PCAST).

Arnold, winner of the 2018 Nobel Prize in Chemistry and the recipient of numerous other honors including the 2011 National Medal of Technology and Innovation and the 2016 Millennium Technology Prize, is a respected pioneer in the fields of protein and chemical engineering. She will serve as co-chair of PCAST, which advises the president on matters involving science, technology, education, and innovation policy. The council also provides the president with scientific and technical information that is needed to inform public policy relating to the American economy, the American worker, national and homeland security, and other topics… Continue reading.

Pope names Nobel-winning U.S. chemical engineer to papal think tank

Via Catholic News Service | October 24, 2019

Pope Francis appointed Frances H. Arnold, a Nobel-winning chemical engineer from the United States, to the Pontifical Academy of Sciences.

Arnold, 63, is the Linus Pauling professor of chemical engineering, biochemistry and bioengineering at the California Institute of Technology and director of its bioengineering center. Her appointment to the papal think tank was announced by the Vatican Oct. 24.

Born in Pittsburgh, Arnold was the co-recipient of the 2018 Nobel Prize in Chemistry for pioneering use of the directed evolution of enzymes… Continue reading.

Enzyme evolved that can perform reactions new to nature

Via Chemistry World | January 10, 2019

Directed evolution has been used to create an enzyme that is capable of forming carbon–carbon bonds in a way that no natural enzyme can. The team, which includes directed evolution pioneer and 2018 chemistry Nobel laureate Frances Arnold, hopes that this strategy can be used to selectively functionalise C–H bonds in a more environmentally friendly manner without the need for precious metals.

C–H activation is regarded as one of the most important strategies in molecular synthesis, as it can unlock a wide range of organic molecules to make drugs and new materials. However, selectively functionalising C–H bonds is a complicated challenge that is usually carried out with precious metal catalysts under harsh conditions in organic solvents… Continue reading.

Nobel Prize in Chemistry Goes to a Woman for the Fifth Time in History

Via New York Times | October 3, 2018

Since 1901, when the Nobel Prize in Chemistry was first awarded, 177 people have captured the honor. On Wednesday, Frances H. Arnold became only the fifth woman to be awarded the prize.

Dr. Arnold, 62, an American professor of chemical engineering, bioengineering and biochemistry at the California Institute of Technology in Pasadena, earned the award for her work with the directed evolution of enzymes.

She shared this year’s chemistry Nobel — worth close to $1 million — with George P. Smith, 77, and Gregory P. Winter, 67. Dr. Arnold received half of the prize, and Dr. Smith and Dr. Winter split the other half… Continue reading.

Frances Arnold, 2011 National Medal of Technology and Innovation

Via National Science & Technology Medals Foundation | January 10, 2011

For pioneering research on biofuels and chemicals that could lead to the replacement of pollution-generating materials.

Frances Arnold has never cared much for ‘tradition.’ As a high schooler, she moved into her own apartment and paid the bills as a waitress and cab driver. As a chemical engineer and biochemist, she has found a groundbreaking way to harness her fierce independence and drive to succeed.

Arnold specializes in the creation of new proteins with an eye towards those that have applications in medicine and clean energy. What makes her stand out in her field is that rather than meticulously create proteins piece by painstaking piece, Arnold has come up with a way to take over from nature and direct evolution.. Continue reading.