Yi-Xian Qin, Ph.D.

AIMBE College of Fellows Class of 2011
For his work in orthopedic biomechanics, which has provided unique insights into the mechanical control of bone repair and remodeling.

Stony Brook Study Shows Ultrasound Triggers Bone Cell Mobility

Via Stony Brook Medicine | July 17, 2012

Research led by Yi-Xian Qin, PhD, Professor, Department of Biomedical Engineering, and Director of the Orthopaedic Bioengineering Research Laboratory at Stony Brook University, demonstrated that the use of medium-intensity focused ultrasound on osteoblasts, known as bone-forming cells, stimulates the mobility of the cells and triggers calcium release, a process that promotes growth. The technique could provide a foundation for a method to develop non-pharmacologic treatments of osteoporosis, fractures, and other conditions involving bone loss. The team’s research findings are detailed online in the PLoS One article “Mechanobiological Modulation of Cytoskeleton and Calcium Influx in Osteoblastic Cells by Short-Term Focused Acoustic Radiation Force.”