Building on prior observations, a meta-regression of published trials has concluded that larger improvements in bone mineral density (BMD) via dual‐energy X‐ray absorptiometry (DXA) are associated with greater reductions in fracture risk, particularly for vertebral and hip fractures. First author Mary Bouxsein, PhD, of the Center for Advanced Orthopedic Studies at Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, and colleagues published their findings in the Journal of Bone and Mineral Research (JBMR).
“Although these results cannot be directly applied to predict the treatment benefit in an individual patient, they provide compelling evidence that improvements in BMD with osteoporosis therapies may be useful surrogate endpoints for fracture in trials of new therapeutic agents,” the authors wrote… Continue reading.
WASHINGTON, D.C.— The American Institute for Medical and Biological Engineering (AIMBE) has announced the pending induction of Mary Larsen Bouxsein, Ph.D., Director, Center for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center and Associate Associate Professor, Harvard Medical School and Faculty, HST Program, Harvard-MIT, Orthopedic Surgery, Harvard Medical School, to its College of Fellows. Dr. Bouxsein was nominated, reviewed, and elected by peers and members of the College of Fellows For contributions to the understanding of fracture occurrence based on bone biomechanics and imaging.