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Stephanie I. Fraley, Ph.D.

AIMBE College of Fellows Class of 2022
For seminal contributions to the understanding of cell-matrix interactions regulating migration and innovations in molecular profiling technology.

DNA Melting Curves Could Speed Blood-Borne Pathogen Detection

Via Genetic Engineering & Biotechnology News | February 21, 2024

Scientists from the University of California, San Diego (UCSD), and elsewhere have described a method of detecting blood-borne pathogens faster and more accurately than traditional blood cultures. The method, called digital DNA melting analysis, produces results in under six hours, much shorter than traditional cultures which can require 15 hours to several days depending on the pathogen.

Details of the method and results from a clinical pilot using blood samples from pediatric patients are provided in the Journal of Molecular Diagnostics in a paper titled, “Universal digital high resolution melt analysis for the diagnosis of bacteremia.” Results from the pilot study showed that their DNA melting approach matched results of blood cultures collected for sepsis testing. They were also able to quantify how much of the pathogen was present in the samples using DNA melting… Continue reading.

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Can rubrics combat gender bias in faculty hiring?

Via Science | June 30, 2022

Some bias persisted, but rubric use should be encouraged

Abstract
Research has documented the presence of bias against women in hiring, including in academic science, technology, engineering, and mathematics (STEM). Hiring rubrics (also called criterion checklists, decision support tools, and evaluation tools) are widely recommended as a precise, cost-effective remedy to counteract hiring bias, despite a paucity of evidence that they actually work (see table S8). Our in-depth case study of rubric usage in faculty hiring in an academic engineering department in a very research-active university found that the rate of hiring women increased after the department deployed rubrics and used them to guide holistic discussions. Yet we also found evidence of substantial gender bias persisting in some rubric scoring categories and evaluators’ written comments. We do not recommend abandoning rubrics. Instead, we recommend a strategic and sociologically astute use of rubrics as a department self-study tool within the context of a holistic evaluation of semifinalist candidates… Get full access to this article.

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Dr. Stephanie Fraley Elected to the 2022 Class of the AIMBE College of Fellows

Via AIMBE | February 18, 2022

WASHINGTON, D.C. — The American Institute for Medical and Biological Engineering (AIMBE) has announced the election of Stephanie I. Fraley, Ph.D., Associate Professor, Bioengineering, University of California, San Diego to its College of Fellows. Dr. Fraley was nominated, reviewed, and elected by peers and members of the AIMBE College of Fellows for seminal contributions to the understanding of cell-matrix interactions regulating migration and innovations in molecular profiling technology.

The College of Fellows is comprised of the top two percent of medical and biological engineers in the country. The most accomplished and distinguished engineering and medical school chairs, research directors, professors, innovators, and successful entrepreneurs comprise the College of Fellows. AIMBE Fellows are regularly recognized for their contributions in teaching, research, and innovation. AIMBE Fellows have been awarded the Nobel Prize, the Presidential Medal of Science and the Presidential Medal of Technology and Innovation, and many also are members of the National Academy of Engineering, National Academy of Medicine, and the National Academy of Sciences… Continue reading.

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