Mikos is the Louis Calder Professor of Bioengineering and Chemical and Biomolecular Engineering and a professor of chemistry, materials science and nanoengineering. His research group at Rice’s BioScience Research Collaborative specializes in the synthesis, processing and evaluation of new biomaterials for use as scaffolds for tissue engineering, as carriers for controlled drug delivery and as nonviral vectors for gene therapy. His work has led to the development of novel orthopedic, dental, cardiovascular, neurologic and ophthalmologic biomaterials. He is the author of more than 520 publications and holds 27 patents.

Mikos is a member of the National Academy of Engineering, the Institute of Medicine of the National Academies and the Academy of Medicine, Engineering and Science of Texas.