Scientists at the University of Pennsylvania say they have developed a novel optical method that uses a pair of macromolecular phosphorescent probes for the real-time monitoring of cerebral metabolic rate of oxygen consumption (CMRO2), concurrently with cerebral blood flow (CBF) in a preclinical animal model. Their study “Real-time tracking of brain oxygen gradients and blood flow during functional activation” appears in Neurophotonics.
CMRO2, which indicates how much energy the brain is consuming at a given time, is a key index of brain activity. Direct quantification of CMRO2 is a significant objective in neurology, as CCMRO2 is a valuable measure of tissue pathology in steady-state conditions, such as those associated with cancer, traumatic brain damage, and stroke… Continue reading.
WASHINGTON, D.C.— The American Institute for Medical and Biological Engineering (AIMBE) has announced the pending induction of Arjun G. Yodh, Ph.D., Professor, Department of Physics and Astronomy, University of Pennsylvania, to its College of Fellows. Dr. Yodh was nominated, reviewed, and elected by peers and members of the College of Fellows For pioneering pre-clinical and clinical contributions to the development of diffuse optics for imaging and monitoring tissue physiology..