Northwestern Medicine scientists have developed a novel high-resolution spatial genomics platform that may enhance future research about how genome organization and genetic alterations contribute to the development of disease, including cancer, as detailed in a recent study published in Nature Methods.
“What is particularly exciting is that we can simultaneously profile 3D genome organization and chromatin accessibility while preserving the native spatial context of cells and tissues, and we can also detect genomic alterations such as copy-number changes and structural variations in cancer,” said co-corresponding author Feng Yue, PhD, the Duane and Susan Burnham Professor of Molecular Medicine and a professor of Biochemistry and Molecular Genetics and of Pathology… Continue reading.
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